Дэниел Киз всегда хотел писать, но родители видели в сыне будущего врача. Он надеялся, что получится заниматься и медициной, и литературой — по примеру Чехова, Моэма и Конана Дойла. «Не успел я так подумать, как понял, где в моём плане слабое место. Прежде чем прославиться на литературной стезе, все трое потерпели фиаско в медицине», — писал автор в книге «Элджернон, Чарли и я».
В итоге Киз получил степень по психологии и английскому языку, а затем оказался в Atlas Comics, будущем Marvel Comics. Там автор работал со Стэном Ли. «Цветы для Элджернона» тоже могли стать графическим романом, но писатель чувствовал: его сюжет больше, чем просто сценарий для фреймов.
Существует версия, что главный герой «Цветов» вдохновлён одним из учеников Дэниела Киза. Школьник был в классе для детей с ограниченными возможностями и как-то спросил писателя, можно ли перевестись, если стать умнее.
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