At an international conference in Prague, Lt. Col. Jon Smith, an Army research doctor specializing in infectious diseases and secretly an agent attached to Covert-One, is contacted by a Russian colleague, Dr. Valentine Petrenko. Petrenko is concerned about a small cluster of mysterious deaths in Moscow and about the Russian government’s refusal to release publicly any information or data on the outbreak. When the two meet, they are attacked by a group of mysterious men and Petrenko is killed, his notes and medical samples are lost, and Smith barely escapes with his life.