New York City, 1896. Hypocrisy in high places is rife, police corruption commonplace, and a brutal killer is terrorising young male prostitutes.
Unfortunately for Police Commissioner Theodore Roosevelt, the psychological profiling of murderers is a practice still in its infancy, struggling to make headway against the prejudices of those who prefer the mentally ill - and the 'alienists' who treat them - to be out of sight as well as out of mind.