In a cafe in modern-day Paris, in the aftermath of a fresh kill, the fearless and beautiful Pandora begins to tell her tale of treachery, vengeance and love stretching across two millennia. As a young mortal in Imperial Rome in the time of Caesar Augustus, Pandora was first introduced to the blood-tainted cult of Isis. Later, in exile in Antioch, she was drawn even further into the dark, ancient rites. Now looking back across the centuries, Pandora decides to return once more to New Orleans, to find the love of her early life, Marius, and to see once again the Vampire Lestat...